HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromomethylnaphthalene → N-(4-Chlorophenyl)-N'-{[4-(2-naphthylmethyl)Morpholin-2-yl]methyl}urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromomethylnaphthalene | HCID 70320 | — |
| Reactant | N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea | HCID 23089254 | — |
| Product | N-(4-Chlorophenyl)-N'-{[4-(2-naphthylmethyl)Morpholin-2-yl]methyl}urea | HCID 10294982 | 34.2% |
Reaction Steps
Example 23 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and 2-(bromomethyl)naphthalene (0.009 g) to give the title compound (0.0052 g). LC-MS (System A): Rt 2.81 mins, Mass Spectrum m/z 410 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-53d6683de43543db964d5c27b9cc2e3c |
| Source note | uspto-grants-2007_01 |