HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloro-4-isocyanatopyridine → N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}N'-(2,6-dichloropyridin-4-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloro-4-isocyanatopyridine | HCID 2781658 | — |
| Reactant | [4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine | HCID 10308229 | — |
| Product | N-{[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}N'-(2,6-dichloropyridin-4-yl)urea | HCID 10183254 | 39.1% |
Reaction Steps
Example 24 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 3 (0.025 g) and 2,6-dichloro-4-isocyanatopyridine (0.0258 g) to give the title compound (0.0165 g). LC-MS (System A): Rt 2.46 mins, Mass Spectrum m/z 463 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-fb45000ffe6b4b209ec323ca48bb05f5 |
| Source note | uspto-grants-2007_01 |