HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Vinylbenzyl chloride → N-(4-Chlorophenyl)-N'-{[4-(4-vinylbenzyl)morpholin-2-yl]methyl}urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Vinylbenzyl chloride | HCID 74126 | — |
| Reactant | N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea | HCID 23089254 | — |
| Product | N-(4-Chlorophenyl)-N'-{[4-(4-vinylbenzyl)morpholin-2-yl]methyl}urea | HCID 10200131 | 49.6% |
Reaction Steps
Example 38 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and 1-(chloromethyl)-4-vinylbenzene (0.0062 g) to give the title compound (0.0071 g). LC-MS (System A): Rt 2.72 mins, Mass Spectrum m/z 386 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-52b7a6f818f241c5ad417b99b1e50794 |
| Source note | uspto-grants-2007_01 |