2-Bromoethyl Benzoate → HCID 17984742, compound

HRID 1371436Notes

Reaction equation

HRID 1371436 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH:11][CH2:12][CH:13]2[O:18][CH2:17][CH2:16][NH:15][CH2:14]2)=[O:10])=[CH:4][CH:3]=1.[C:19]([O:27][CH2:28][CH2:29]Br)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:19]([O:27][CH2:28][CH2:29][N:15]1[CH2:16][CH2:17][O:18][CH:13]([CH2:12][NH:11][C:9]([NH:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)=[O:10])[CH2:14]1)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 5230902-Bromoethyl BenzoateHCID 23089254N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea

Product 1

HCID 17984742HCID 17984742, compound

Procedure

Example 39 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and 2-bromoethyl benzoate (6.5 μl) to give the title compound (0.007 g). LC-MS (System A): Rt 2.69 mins, Mass Spectrum m/z 418 [MH+].

Workup

  1. customExample 39 was prepared in an analogous manner to Example 19 using

Sources & evidence

ORD record
ord-7a260be1bf7a499bbe57e2394c260a9b
Source dataset
uspto-grants-2007_01
Patent number
US07157457B2

Reaction notes

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