HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4'-Dichlorobutyrophenone → N-(4-Chlorophenyl)-N'-({4-[4-(4-chlorophenyl)-4-oxobutyl]morpholin-2-yl)methyl}urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4'-Dichlorobutyrophenone | HCID 2723781 | — |
| Reactant | N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea | HCID 23089254 | — |
| Product | N-(4-Chlorophenyl)-N'-({4-[4-(4-chlorophenyl)-4-oxobutyl]morpholin-2-yl)methyl}urea | HCID 10204250 | 25.8% |
Reaction Steps
Example 41 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and 4-chloro-1-(4-chlorophenyl)butan-1-one (0.0089 g) to give the title compound (0.0043 g). LC-MS (System A): Rt 2.83 mins, Mass Spectrum m/z 450 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-509bb4ea55d04628ab541ed5af7cd48d |
| Source note | uspto-grants-2007_01 |