Bromoacetonitrile → HCID 9857806, compound

HRID 1371442Notes

Reaction equation

HRID 1371442 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH:11][CH2:12][CH:13]2[O:18][CH2:17][CH2:16][NH:15][CH2:14]2)=[O:10])=[CH:4][CH:3]=1.Br[CH2:20][C:21]#[N:22]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH:11][CH2:12][CH:13]2[O:18][CH2:17][CH2:16][N:15]([CH2:20][C:21]#[N:22])[CH2:14]2)=[O:10])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 11534BromoacetonitrileHCID 23089254N-(4-Chlorophenyl)-N'-(morpholin-2-ylmethyl)urea

Product 1

HCID 9857806HCID 9857806, compound

Procedure

Example 46 was prepared in an analogous manner to Example 19 using a mixture of Intermediate 9 (0.01 g) and bromoacetonitrile (2.8 μl) to give the title compound (0.0039 g).

Workup

  1. customExample 46 was prepared in an analogous manner to Example 19 using

Sources & evidence

ORD record
ord-2590f275556148afa1385b857f7ca212
Source dataset
uspto-grants-2007_01
Patent number
US07157457B2

Reaction notes

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