HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 10269632, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 4-Nitrophenyl [4-(3,4-dichlorobenzyl)morpholin-2-yl]methylcarbamate | HCID 11539448 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 10269632 | HCID 10269632 | 86.5% |
Reaction Steps
Example 56 was prepared in an analogous manner to Example 43 from Intermediate 10 (0.040 g) and propargylamine (0.006 g) using dichloromethane and triethylamine at a temperature of 22° C. to yield the title compound (0.028 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157457B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-87295676fc934a76bf08af245f7bb1fb |
| Source note | uspto-grants-2007_01 |