Sulfuric Acid → HCID 178448881, compound

HRID 1371469Notes

Reaction equation

HRID 1371469 reaction equation
[S:1](=[O:5])(=[O:4])([OH:3])[OH:2].[CH2:6]([NH:10][C:11]1[N:19]=[C:18]2[C:14]([N:15]=[C:16]([OH:28])[N:17]2[CH2:20][C:21]2[CH:22]=[N:23][C:24]([CH3:27])=[CH:25][CH:26]=2)=[C:13]([NH2:29])[N:12]=1)[CH2:7][CH2:8][CH3:9]>CO>[S:1]([OH:5])([OH:4])(=[O:3])=[O:2].[CH2:6]([NH:10][C:11]1[N:19]=[C:18]2[C:14]([N:15]=[C:16]([OH:28])[N:17]2[CH2:20][C:21]2[CH:22]=[N:23][C:24]([CH3:27])=[CH:25][CH:26]=2)=[C:13]([NH2:29])[N:12]=1)[CH2:7][CH2:8][CH3:9]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 178448880HCID 178448880, compound

Product 1

HCID 178448881HCID 178448881, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.5N sulfuric acid (30.8 ml) was added to a methanol solution (520 ml) of the compound of Example 27 (2.52 g, 7.70 mmol), and the precipitated crystal was collected by filtration. Thus, the title compound was obtained.

Workup

  1. filtrationthe precipitated crystal was collected by filtration

Sources & evidence

ORD record
ord-7a111b1a6aea4135a35d1c16d3088299
Source dataset
uspto-grants-2007_01
Patent number
US07157465B2

Reaction notes

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