HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propyl isocyanate → HCID 10476781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propyl isocyanate | HCID 61033 | — |
| Reactant | [4-Amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(2-methoxy-phenyl)-methanone trifluoroacetic acid salt | HCID 69014044 | — |
| Product | HCID 10476781 | HCID 10476781 | — |
Reaction Steps
The same procedure as described in Example 25 was used, starting from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(2-methoxy-phenyl)-methanone trifluoroacetic acid salt, Example 11, and propyl isocyanate (Aldrich), to give 4-[4-Amino-5-(2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidine-1-carboxylic acid propylamide. HRMS, observed: 413.2299; Calcd for (M+H)+: 413,2296.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-abfb8c0e48154c62832efc9271a3ae03 |
| Source note | uspto-grants-2007_01 |