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HRID1371630

反应详情

EQUATION

反应方程式

HRID 1371630 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1CC[C@H](N)C1
HCID854071

tert-Butyl (3S)-3-aminopyrrolidine-1-carboxylate

C9H18N2O2

结构：CCS(=O)(=O)c1ncc(C(=O)c2cc(F)ccc2OC)c(N)n1
HCID10472348

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(F)cc1C(=O)c1cnc(N[C@H]2CCN(C(=O)OC(C)(C)C)C2)nc1N
HCID58777617

未命名化合物

PROCEDURE

实验过程

The same procedure was used as described in Example 9 starting from (4-amino-2-ethanesulfonyl-pyrimidin-5-yl)-(5-fluoro-2-methoxy-phenyl)-methanone, Example 48, and (S)-3-amino-pyrrolidine-1-carboxylic acid tert-butyl ester (Astatech), to give (S)-3-[4-amino-5-(5-fluoro-2-methoxy-benzoyl)-pyrimidin-2-ylamino]-pyrrolidine-1-carboxylic acid tert-butyl ester. MS (M+H)+, 432.