HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Methanesulfonyl)piperidin-4-amine → RO-4584820
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Methanesulfonyl)piperidin-4-amine | HCID 11355826 | — |
| Reactant | HCID 11975080 | HCID 11975080 | — |
| Product | RO-4584820 | HCID 6918852 | — |
Reaction Steps
The same procedure as described in Example 90 was used, starting from (4-amino-2-ethanesulfonyl-pyrimidin-5-yl)-(2,3-difluoro-6-methoxy-phenyl)-methanone, Example 103, and 1-methanesulfonyl-piperidin-4-ylamine (with trifluoro-acetic acid), Example 162, to give [4-amino-2-(1-methanesulfonyl-piperidin-4-ylamino)-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone. MS (M+H)+, 442.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-8fd3bce57c654eefa259b84d6552484f |
| Source note | uspto-grants-2007_01 |