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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371659Generated: November 1, 2026

1,3,5-trimethyl-1H-pyrazole-4-sulfonyl chloride → HCID 58777591, compound

https://huagongshe.com/reaction/1371659

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3,5-trimethyl-1H-pyrazole-4-sulfonyl chlorideHCID 2737340—
Reactant[4-Amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanoneHCID 9997668—
ProductHCID 58777591HCID 58777591—

Reaction Steps

The title compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone, Example 59, and 1,3,5-trimethyl-1H-pyrazole-4-sulfonyl chloride (Maybridge) by the procedure described in Example 152. HR-MS (ES, m/z) calculated for C23H28FN7O4S [(M+H)+] 518.1981, observed 518.1986.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-3b5d46879eed4e6d8dad3c1caf02ea9c
Source noteuspto-grants-2007_01