HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-fluorotoluene → (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(5-fluoro-2-methyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-fluorotoluene | HCID 74016 | — |
| Reactant | 5-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl- | HCID 11974832 | — |
| Product | (4-Amino-2-ethylsulfanyl-pyrimidin-5-yl)-(5-fluoro-2-methyl-phenyl)-methanone | HCID 21070590 | — |
Reaction Steps
The compound was prepared from 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide, Example 1, and 2-bromo-4-fluorotoluene (Aldrich) in an analogous manner as described in Example 169.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-593e21034e2a43189d24606ff415c596 |
| Source note | uspto-grants-2007_01 |