HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-butanol, (-)- → HCID 58777606, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-butanol, (-)- | HCID 2723856 | — |
| Reactant | [4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone | HCID 9983584 | — |
| Product | HCID 58777606 | HCID 58777606 | — |
Reaction Steps
The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 226) and (R)-2-amino-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H35N6O5SF2 [(M+H)+] 557.2352, observed 557.2360.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-888651fcbf734bd689d465d72a63c885 |
| Source note | uspto-grants-2007_01 |