Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371698Generated: October 31, 2026

Pyrrolidine → HCID 10052966, compound

https://huagongshe.com/reaction/1371698

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanoneHCID 9983584—
ProductHCID 10052966HCID 10052966—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 226) and pyrrolidine (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H33N6O4SF2 [(M+H)+] 539.2247, observed 539.2252.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-822a0a3bf5ee4ab3a868d2998cab7ba1
Source noteuspto-grants-2007_01