Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371699Generated: October 31, 2026

Morpholine → HCID 10347630, compound

https://huagongshe.com/reaction/1371699

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanoneHCID 9983584—
ProductHCID 10347630HCID 10347630—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 226) and morpholine (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H33N6O5SF2 [(M+H)+] 555.2196, observed 555.2199.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-06a9b6666a714c14b0890ad82195d953
Source noteuspto-grants-2007_01