Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371705Generated: November 2, 2026

D-Valinol → HCID 10460662, compound

https://huagongshe.com/reaction/1371705

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-ValinolHCID 6950587—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanoneHCID 9983584—
ProductHCID 10460662HCID 10460662—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(2,3-difluoro-6-methoxy-phenyl)-methanone (Example 226) and (R)-2-amino-3-methyl-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C25H37N6O5SF2 [(M+H)+] 571.2509, observed 571.2514.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-de6dea750a6148238396c0b88dda18d7
Source noteuspto-grants-2007_01