HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1-butanol, (-)- → HCID 10370001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1-butanol, (-)- | HCID 2723856 | — |
| Reactant | [4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone | HCID 10458099 | — |
| Product | HCID 10370001 | HCID 10370001 | — |
Reaction Steps
The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 242) and (R)-2-amino-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C24H36N6O5SF [(M+H)+] 539.2450, observed 539.2447.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-cf9f7128bec84b49b819b97d3a43999f |
| Source note | uspto-grants-2007_01 |