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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371715Generated: November 3, 2026

D-Valinol → HCID 10325324, compound

https://huagongshe.com/reaction/1371715

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-ValinolHCID 6950587—
Reactant[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanoneHCID 10458099—
ProductHCID 10325324HCID 10325324—

Reaction Steps

The compound was prepared from [4-amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 242) and (R)-2-amino-3-methyl-1-butanol (Aldrich) in an analogous manner as described in Example 227. HR-MS (ES, m/z) calculated for C25H38N6O5SF [(M+H)+] 553.2603, observed 553.2600.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-4802a6ddb5df4b6981a9be5d673a8e0c
Source noteuspto-grants-2007_01