HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobutane-1-sulphonyl chloride → HCID 58777553, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobutane-1-sulphonyl chloride | HCID 74212 | — |
| Reactant | [4-Amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone | HCID 9997668 | — |
| Product | HCID 58777553 | HCID 58777553 | — |
Reaction Steps
The compound was prepared from [4-amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone (Example 59) and 4-chloro-butane-1-sulfonyl chloride (Example 254) in an analogous manner as described in Example 177. HR-MS (ES, m/z) calculated for C21H27N5O4SFCI [(M+H)+] 500.1532, observed 500.1529.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157455B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-22142b71c380435db2e0824c2734eaa3 |
| Source note | uspto-grants-2007_01 |