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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371806Generated: October 31, 2026

5-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl- → HCID 21070585, compound

https://huagongshe.com/reaction/1371806

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-HCID 11974832—
ReactantHCID 178418676HCID 178418676—
ProductHCID 21070585HCID 21070585—

Reaction Steps

The same procedure as described in Example 353 was used, starting from 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide (Example 1) and 4-fluorophenyl magnesium bromide (Aldrich) to give (4-amino-2-ethylsulfanyl-pyrimidin-5-yl)-(4-fluoro-phenyl)-methanone. MS (M+H)+, 278.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-91a06f43ba6f476894f30040baf49338
Source noteuspto-grants-2007_01