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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1371809Generated: October 31, 2026

4-Bromo-2-fluoroanisole → HCID 21070579, compound

https://huagongshe.com/reaction/1371809

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-2-fluoroanisoleHCID 75378—
Reactant5-Pyrimidinecarboxamide, 4-amino-2-(ethylthio)-N-methoxy-N-methyl-HCID 11974832—
ProductHCID 21070579HCID 21070579—

Reaction Steps

The same procedure as described in Example 47 was used, starting from 4-amino-2-ethylsulfanyl-pyrimidine-5-carboxylic acid methoxy-methyl-amide (Example 1) and 4-bromo-2-fluoroanisole (Aldrich), to give (4-amino-2-ethylsulfanyl-pyrimidin-5-yl)-(3-fluoro-4-methoxy-phenyl)-methanone as a white solid. MS (M+H)+, 308.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07157455B2
Source datasetuspto-grants-2007_01
ORD IDord-f845a36610a74d84bb9c0ccba49fbdec
Source noteuspto-grants-2007_01