[1-(Methylsulfonyl)piperidin-4-yl]amine trifluoroacetate → HCID 58777548, compound

Participants

Reaction Steps

The same procedure as described in Example 326 was used, starting with (4-amino-2-ethanesulfinyl-pyrimidin-5-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone (Example 377) and 1-methanesulfonyl-piperidin-4-ylamine; compound with trifluoroacetic acid (Example 162) to give [4-amino-2-(1-methanesulfonyl-piperidin-4-ylamino)-pyrimidin-5-yl]-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone as a white solid. MS (M+H)+, 458.

Provenance & Evidence