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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137198Generated: October 25, 2026

Chloride → 4-Chloro-6-(2,6-difluorobenzyl)pyrimidine

https://huagongshe.com/reaction/137198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
Reactant1,1-DibromoethaneHCID 11201—
ReactantZincHCID 23994—
ReactantTrimethylsilaneHCID 70435—
Reactant4,6-DichloropyrimidineHCID 70943—
Reactant2-(Bromomethyl)-1,3-difluorobenzeneHCID 581435—
Product4-Chloro-6-(2,6-difluorobenzyl)pyrimidineHCID 22599701—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-2a6e8e4f65934776a9ca6880551126f1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)