Dimethylformamide → HCID 21071055, compound

Participants

Reaction Steps

Protocol T was followed using 4-Chloro-3-(4-Fluoro-phenyl)-5-methylsulfanyl-1H-pyrazole, K2CO3, 2-Chloro-1-[4-(4-fluoro-phenyl)-piperazin-1-yl]-ethanone and DMF. Column chromatography using a solvent mixture (hexane/ethyl acetate=2/3) afforded the title compound as white solid. 1H NMR (400 MHz, CDCl3): 7.46–7.5 (m, 2H), 7.12–7.18 (m, 2H), 6.96–7.1 (m, 2H), 6.88–6.92 (m, 2H), 4.86 (s, 2H), 3.72–3.78 (m, 2H), 3.56–3.62 (m, 2H), 3.06–3.18 (m, 4H), 2.54 (s, 3H).

Provenance & Evidence