Dimethylformamide → HCID 68424018, compound

Participants

Reaction Steps

Protocol T was followed using 4-Chloro-3-Thiophen-2-yl-2H-pyrazole-5-carboxylic acid ethyl ester, K2CO3, 2-Chloro-1-[4-(4-fluoro-phenyl)-piperazin-1-yl]-ethanone and DMF. Column chromatography using a solvent mixture (hexane/ethyl acetate=1.5/1:Rf=0.62) afforded the title compound. 1H NMR (400 MHz, CDCl3): 7.06–7.36 (m, 1H), 6.96–7.2 (m, 3H), 6.84–6.92 (m, 3H), 54.46 (s, 2H), 4.3–4.4 (q, 2H), 3.6–3.82 (m, 4H), 3.05–3.25 (m, 4H), 1.3–1.42 (m, 3H).

Provenance & Evidence