1-Pyrrolidineethanamine → HCID 21071887, compound

HRID 1372389Notes

Reaction equation

[CH:1]([C:3]1[NH:7][C:6]([CH3:8])=[C:5]([CH2:9][C:10]([OH:12])=O)[C:4]=1[CH3:13])=[O:2].[NH2:14][CH2:15][CH2:16][N:17]1[CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH:1]([C:3]1[NH:7][C:6]([CH3:8])=[C:5]([CH2:9][C:10]([NH:14][CH2:15][CH2:16][N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)=[O:12])[C:4]=1[CH3:13])=[O:2]

Participants

Reactant 2

HCID 13441-Pyrrolidineethanamine

HCID 221354182-(5-Formyl-2,4-dimethyl-1H-pyrrol-3-YL)acetic acid

Product 1

HCID 21071887HCID 21071887, compound

Procedure

(5-Formyl-2,4-dimethyl-1H-pyrrol-3-yl)-acetic acid was reacted with 1-(2-aminoethyl)pyrrolidine using General Amidation Procedure 1 to give 2-(5-formyl-2,4-dimethyl-1H-pyrrol-3-yl)-N-(2-pyrrolidin-1-yl-ethyl)-acetamide. MS m/z 278 [M+1].

Sources & evidence

ORD record: ord-ed9db7f6a6d640b48529f32c7cbbcc90
Source dataset: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07157577B2

Reaction notes

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