Sodium Hydroxide → HCID 17859065, compound

Participants

Reaction Steps

In THF (5 ml) was dissolved methyl (4-(2-benzothiazolyl)amino-3-chlorophenyl)acetate (296 mg, 0.89 mmol). To the resulting solution was added 0.5N NaOH (5.0 ml, 2.50 mmol). The resulting mixture was stirred at room temperature for 15 hours. The reaction mixture was poured in ice-1N HCl to acidify the mixture. The crystals thus precipitated were collected by filtration under reduced pressure, washed with water and dried under reduced pressure to give (4-(2-benzothiazolyl)amino-3-chlorophenyl)acetic acid (263 mg, 93%) as a white solid.

Provenance & Evidence