Trifluoroacetic acid → HCID 17858872, compound

Participants

Reaction Steps

In methylene chloride (20 ml) was dissolved tert-butyl (4-((2-indolylcarbonyl)amino)-3-methoxyphenyl)acetate (1.31 g, 3.44 mmol). To the resulting solution was added TFA (10 ml) at 0° C. After the reaction mixture was stirred at room temperature for 1 hour, the reaction mixture was distilled under reduced pressure to remove the solvent, whereby (4-((2-indolylcarbonyl)amino)-3-methoxyphenyl)acetic acid (1.11 g, 99%) was obtained as a brown solid.

Provenance & Evidence