HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 729944, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | D-Tartaric acid | HCID 439655 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 729944 | HCID 729944 | 84,635.797% |
Reaction Steps
In xylene (500 ml), D-tartaric acid (25.0 g, 0.17 mol) and benzylamine (19.6 g, 0.18 mmol) were heated under reflux for 18 hours by using a Dean-Stark water separator. After cooling, the reaction mixture was distilled under reduced pressure to remove the solvent, whereby 1-benzyl-(3S,4S)-dihydroxy-2,5-dioxopyrrolidine (33.7 g, 90%) was obtained as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07157487B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-1eb2cd00b5fd4c80b06b7c3c0a6d6cf7 |
| Source note | uspto-grants-2007_01 |