Ethyl Bromide → Butyl ether

Participants

Reaction Steps

21.4 g (0.880 mol) of magnesium and 125.0 g (0.960 mol) of dibutyl ether were charged in a 1,000 ml flask equipped with a reflux condenser, a dropping funnel and a stirring apparatus, in an atmosphere of nitrogen, and after stirring was started, a solution having 172.1 g (0.800 mol) of 1-bromoadamantane and 4.36 g (0.0400 mol) of ethyl bromide diluted with 250.0 g (1.92 mol) of dibutyl ether was dropwise added thereto from the dropping funnel over a period of 2 hours under reflux of dibutyl ether, and then stirring was carried out for 4 hours under reflux of dibutyl ether, to obtain a dibutyl ether solution of 1-adamantyl magnesium bromide.

Provenance & Evidence