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HRID1372949

反应详情

EQUATION

反应方程式

HRID 1372949 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)[C@@](C)(F)C(=O)O
HCID13350487

未命名化合物

结构：N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21
HCID68916092

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)[C@@](C)(F)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21
HCID69039501

未命名化合物

PROCEDURE

实验过程

(S)-7-amino-5-cyclopropylmethyl-5H,7H-dibenzo[b,d]azepin-6-one was coupled with (S)-2-fluoro-2-methyl-malonic acid monoethyl ester in analogy to the description in example 73 to yield (S)-N-((S)-5-cyclopropylmethyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-2-fluoro-2-methyl-malonamic acid ethyl ester as colourless oil.