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HRID1372951

反应详情

EQUATION

反应方程式

HRID 1372951 的结构方程式

REACTANTS

反应物

2
结构：NCC(F)(F)C(F)(F)F
HCID79002

1H,1H-Perfluoropropylamine

C3H4F5N

结构：C[C@@](F)(C(=O)O)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21
HCID69043616

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@](F)(C(=O)NCC(F)(F)C(F)(F)F)C(=O)N[C@@H]1C(=O)N(CC2CC2)c2ccccc2-c2ccccc21
HCID21072479

未命名化合物

PROCEDURE

实验过程

(S)-N-((S)-5-cyclopropylmethyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-2-fluoro-2-methyl-malonamic acid was coupled with 2,2,3,3,3-pentafluoropropylamine in analogy to the procedure described for RJR 7 to yield (R)-N-((S)-5-cyclopropylmethyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-2-fluoro-2-methyl-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide as white solid.