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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1372952Generated: October 31, 2026

2-methoxy-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid → HCID 86596823, compound

https://huagongshe.com/reaction/1372952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methoxy-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acidHCID 21072493—
ReactantHCID 68916092HCID 68916092—
ProductHCID 86596823HCID 86596823—

Reaction Steps

(S)-7-amino-5-cyclopropylmethyl-5H,7H-dibenzo[b,d]azepin-6-one was coupled with 2-methoxy-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid in analogy to the description in example 73 to yield N-((S)-5-cyclopropylmethyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-2-methoxy-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07160875B2
Source datasetuspto-grants-2007_01
ORD IDord-f3e19859661d479094610b7e4c80848d
Source noteuspto-grants-2007_01