HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-methoxy-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid → HCID 86596833, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-methoxy-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid | HCID 21072493 | — |
| Reactant | (7S)-7-Amino-5,7-dihydro-5-methyl-6H-dibenz[b,d]azepin-6-one | HCID 59100698 | — |
| Product | HCID 86596833 | HCID 86596833 | — |
Reaction Steps
(S)-7-Amino-5-methyl-5H,7H-dibenzo[b,d]azepin-6-one was coupled with 2-methoxy-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid in analogy to the description in example 73 to yield 2-methoxy-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide as white solid. [α] 589=−71.8° (1% in CHCl3), MS m/e (%): 486.4 (M+H+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160875B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-e666f336ed624f46ad5efc7224f0d073 |
| Source note | uspto-grants-2007_01 |