反应详情

In an analogous manner to that described in Example 25 a), the alkylation of the (S)-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4] diazepin-3-yl)-carbamic acid tert-butyl ester with 2,2,2-trifluoroethyl triflate, yielded, after chromatography on silica gel using a 98:2-mixture of dichloromethane and methanol as the eluent, the title compound as a white solid;

1. customyielded