Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 23020498 | HCID 23020498 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 23020494 | HCID 23020494 | — |
Reaction Steps
To a solution of 3-allyl-2-amino-6-(3-fluorophenyl)-5-(6-oxo-1,6-dihydro-3-pyridinyl)-3,4-dihydro-4-pyrimidinone in dimethyl sulfoxide were added potassium carbonate (2 equivalents) and iodomethane (4 equivalents), followed by stirring at 50° C. for 16 hours. After filtering off the insoluble matters, the filtrate was purified by HPLC, to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07160892B2 |
|---|
| Source dataset | uspto-grants-2007_01 |
|---|
| ORD ID | ord-9a493c5e130045d5b2d7e9f9fa3db55c |
|---|
| Source note | uspto-grants-2007_01 |
|---|
