m-Chloroperbenzoic acid → HCID 69431609, compound

Participants

Reaction Steps

The 5-nitro-4-vinylisoquinoline (23 g) obtained in Step A mentioned above was dissolved in dichloromethane (400 ml), then slowly added with m-chloroperbenzoic acid (43 g, Tokyo Kasei Kogyo), and stirred for 3.5 hours. The reaction mixture was cooled on ice, and then neutralized by addition of saturated aqueous sodium hydrogencarbonate. Then, the organic layer was separated, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to obtain the title compound (27 g).

Provenance & Evidence