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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137308Generated: October 29, 2026

N,N-Dimethylaniline → 4-Chloro-6-(trifluoromethyl)pyrimidin-2-amine

https://huagongshe.com/reaction/137308

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-DimethylanilineHCID 949—
ReactantWaterHCID 962—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178508973HCID 178508973—
Product4-Chloro-6-(trifluoromethyl)pyrimidin-2-amineHCID 13086907—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-77a1a266245c48789cedb5793b4a0c11
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)