Oxalyl chloride → Propanoic acid, 3-chloro-3-oxo-, phenylmethyl ester

Participants

Reaction Steps

To the solution of commercially available mono-benzyl malonate (Aldrich Chemical Co., Milwaukee, Wis.) (7.76 g, 40 mmol) in methylene chloride (100 mL) was added oxalyl chloride (14 mL, 160 mmol) followed by 3 drops of dimethylformamide. The reaction mixture was stirred at room temperature for 3 hours and concentrated in vacuo.

Provenance & Evidence