HRID1373097

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)=CC[C@@H]1C[C@@H]([C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)OC1=O

HCID12015737

未命名化合物

结构：C[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NC1CC2CCC1C2

HCID86596503

未命名化合物

PRODUCTS

生成物

结构：CC(C)=CC[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NC1CC2CCC1C2

HCID69507684

未命名化合物

收率 60%

PROCEDURE

实验过程

{(S)-1-[(2S,4R)-4-(3-Methyl-but-2-enyl)-5-oxo-tetrahydro-furan-2-yl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester (D5) was treated with (±)exo-norbornylamine as described in D3 to afford D6 as a white solid (60%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b2ed7cc5fe3641929660154b8213a09f
来源数据集: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07160905B2
来源说明: uspto-grants-2007_01

反应 SMILES

[C:1]([O:5][C:6](=[O:27])[NH:7][C@H:8]([C@@H:16]1[CH2:20][C@@H:19]([CH2:21][CH:22]=[C:23]([CH3:25])[CH3:24])[C:18](=[O:26])[O:17]1)[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)([CH3:4])([CH3:3])[CH3:2].[CH:28]12[CH2:34][CH:31]([CH2:32][CH2:33]1)[CH2:30][CH:29]2[NH:35]C(=O)[C@H](C)C[C@H](O)[C@@H](NC(OC(C)(C)C)=O)CC1C=CC=CC=1>>[C:1]([O:5][C:6](=[O:27])[NH:7][C@@H:8]([CH2:9][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)[C@@H:16]([OH:17])[CH2:20][C@H:19]([C:18](=[O:26])[NH:35][CH:29]1[CH2:30][CH:31]2[CH2:34][CH:28]1[CH2:33][CH2:32]2)[CH2:21][CH:22]=[C:23]([CH3:25])[CH3:24])([CH3:2])([CH3:3])[CH3:4]