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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1373099Generated: October 30, 2026

(2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amide → (2R,4S,5S)-5-Amino-4-hydroxy-2-(3-methyl-butyl)-6-phenyl-hexanoic acid bicyclo[2.2.1]hept-2-ylamide

https://huagongshe.com/reaction/1373099

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amideHCID 68889549—
Reactant[(1S,2S,4R)-1-Benzyl-4-(bicyclo[2.2.1]hept-2-ylcarbamoyl)-2-hydroxy-7-methyl-octyl]carbamic acid tert-butyl esterHCID 69508375—
Product(2R,4S,5S)-5-Amino-4-hydroxy-2-(3-methyl-butyl)-6-phenyl-hexanoic acid bicyclo[2.2.1]hept-2-ylamideHCID 69507585—

Reaction Steps

D8 was prepared from D7 by the method described in D4, as a white foam (100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07160905B2
Source datasetuspto-grants-2007_01
ORD IDord-f0708453b94e451ea24ee1dabb2ecb53
Source noteuspto-grants-2007_01