HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amide → (2R,4S,5S)-5-Amino-4-hydroxy-2-(3-methyl-butyl)-6-phenyl-hexanoic acid bicyclo[2.2.1]hept-2-ylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amide | HCID 68889549 | — |
| Reactant | [(1S,2S,4R)-1-Benzyl-4-(bicyclo[2.2.1]hept-2-ylcarbamoyl)-2-hydroxy-7-methyl-octyl]carbamic acid tert-butyl ester | HCID 69508375 | — |
| Product | (2R,4S,5S)-5-Amino-4-hydroxy-2-(3-methyl-butyl)-6-phenyl-hexanoic acid bicyclo[2.2.1]hept-2-ylamide | HCID 69507585 | — |
Reaction Steps
D8 was prepared from D7 by the method described in D4, as a white foam (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160905B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-f0708453b94e451ea24ee1dabb2ecb53 |
| Source note | uspto-grants-2007_01 |