HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amide → (2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid cyclohexylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amide | HCID 68889549 | — |
| Reactant | (2R,4S,5S)-5-t-Butoxycarbonylamino-4-hydroxy-2-methyl-6-phenylhexanoic acid cyclohexylamide | HCID 69507886 | — |
| Product | (2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid cyclohexylamide | HCID 69508038 | — |
Reaction Steps
(2R,4S,5S)-5-t-Butoxycarbonylamino-4-hydroxy-2-methyl-6-phenylhexanoic acid cyclohexylamide (D9) (9.43 g) was deprotected in an analogous fashion to D4 to give D10 as a white solid (2 crops, 5.53 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160905B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-0f92e76e5b09461182fabca64ccd569d |
| Source note | uspto-grants-2007_01 |