反应详情

8.0 g (24.2 mmol) of 1-acetyl-5-phenylsulphonylamino-2-indolinone are dissolved in 150 ml of acetic anhydride and after the addition of 20 ml (88.1 mmol) of triethyl orthobenzoate refluxed for 6 hours. The solvent is distilled off, the residue is triturated with ether, suction filtered and dried.

1. temperaturerefluxed for 6 hours
2. distillationThe solvent is distilled off
3. customthe residue is triturated with ether, suction
4. filtrationfiltered
5. customdried