HCID 15508064, compound → HCID 15508065, compound

Participants

Reaction Steps

10% carbon-palladium (4 g) was added to an ethanol solution of tert-butyl[4-(2-nitrophenylamino)benzyl]carbamate (36 g, 105 mmols). The resulting mixture was hydrogenated at room temperature under atmospheric pressure for 4 hours. The catalyst was removed through filtration, and the filtrate was concentrated under reduced pressure. The residual solid was recrystallized from hexane/ethyl acetate to give a crystal of tert-butyl[4-(2-aminophenylamino)benzyl]carbamate (29.5 g, 89.9%).

Provenance & Evidence