HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate → HCID 22140744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate | HCID 2764081 | — |
| Reactant | HCID 135830927 | HCID 135830927 | — |
| Product | HCID 22140744 | HCID 22140744 | 69.5% |
Reaction Steps
Using an analogous procedure to that described in Example 12, 4-(2,4-dichloro-5-methoxyanilino)-7-hydroxy-5-tetrahydropyran-4-yloxyquinazoline (0.109 g) was reacted with 1-tert-butoxycarbonylpiperidin-4-ylmethanol (0.065 g) to give 4-(2,4-dichloro-5-methoxyanilino)-7-(1-tert-butoxycarbonylpiperidin-4-ylmethoxy)-5-tetrahydropyran-4-yloxyquinazoline (0.11 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160891B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-38ccaba9c5b849bbb997bab49834d0a4 |
| Source note | uspto-grants-2007_01 |