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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 137346Generated: October 29, 2026

Hydrochloric Acid → 4-(4-Chloro-phenyl)-1-[1-(5,6-dimethyl-2-trifluoromethyl-pyrimidin-4-yl)-4-hydroxy-pyrrolidin-3-yl]-piperidin-4-ol

https://huagongshe.com/reaction/137346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-Chloro-5,6-dimethyl-2-(trifluoromethyl)pyrimidineHCID 2736503—
Reactant4-(4-Chlorophenyl)-1-(4-hydroxy-pyrrolidin-3-yl)-piperidin-4-olHCID 66967964—
Product4-(4-Chloro-phenyl)-1-[1-(5,6-dimethyl-2-trifluoromethyl-pyrimidin-4-yl)-4-hydroxy-pyrrolidin-3-yl]-piperidin-4-olHCID 58683572—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-44b63c12868e4b0989dba9031f051915
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)