Potassium Permanganate → HCID 69410961, compound

HRID 1373477Notes

Reaction equation

HRID 1373477 reaction equation
[Mn]([O-])(=O)(=O)=[O:2].[K+].[CH:7]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH:15]=[C:14]([CH2:17][CH2:18][NH:19][C:20](=[O:22])[CH3:21])[C:13]=2[CH:23]=1)=[O:8]>CC(C)=O.O.CC(C)=O>[C:20]([NH:19][CH2:18][CH2:17][C:14]1[C:13]2[CH:23]=[C:9]([C:7]([OH:2])=[O:8])[CH:10]=[CH:11][C:12]=2[O:16][CH:15]=1)(=[O:22])[CH3:21]

Participants

5

Reactant 2

HCID 516875Potassium PermanganateHCID 18360675HCID 18360675, compound

Product 1

HCID 69410961HCID 69410961, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

2.7 g of potassium permanganate in 50 ml of an acetone/water mixture (50/50) are added at ambient temperature to a solution of 6.88 mmol of the product obtained in Step D in 30 ml of acetone. The solution is stirred for 2 hours at ambient temperature and then filtered. The filtrate is concentrated under reduced pressure and chromatographed on silica gel to yield the title product.

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate is concentrated under reduced pressure
  3. customchromatographed on silica gel

Sources & evidence

ORD record
ord-16a1664fc4454438b0b0c00024e1cc60
Source dataset
uspto-grants-2007_01
Patent number
US07161035B2

Reaction notes

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