HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-((7-Oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)oxy)butanal → HCID 21073718, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-((7-Oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)oxy)butanal | HCID 21073377 | — |
| Reactant | HCID 21073422 | HCID 21073422 | — |
| Product | HCID 21073718 | HCID 21073718 | — |
Reaction Steps
In a manner similar to that of other examples above, 5-piperazin-1-yl-3,4-dihydro-2H-naphthalen-1-one was coupled by reductive amination to 4-(7-oxo-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yloxy)-butyraldehyde followed by typical workup and purification to give the title compound, mp 169–170° C. MS: APCI: M+1: 449.2 (Exact Mass: 448.25).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07160888B2 |
| Source dataset | uspto-grants-2007_01 |
| ORD ID | ord-ce9c7079849845579a3a234a6646e0d6 |
| Source note | uspto-grants-2007_01 |