HCID 21073257, compound → HCID 21073471, compound

Participants

Reaction Steps

2-Benzyloxy-7-{3-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-propoxy}-[1,8]naphthyridine (367 mg, 0.701 mmol) was hydrogenated using 5% Pd/C (0.1 g) in MeOH (50 mL) for 1 h. The reaction was filtered and concentrated. Purification by liquid chromatography (4–5% MeOH/CH2Cl2) gave the title compound as a white foam (181 mg, 0.418 mmol, 60%). MS: APCI: M+1: 433.1 (Exact Mass: 432.11).

Provenance & Evidence